A study published in 2010 in the Swiss Medical Weekly found that a smokefree law in the Canton of Graubünden, Switzerland, resulted in fewer heart attacks in the first year after its implementation. The law took effect on March 1, 2008. In the first year following its implementation, there was an overall 22% reduction in incidences of acute myocardial infarction (AMI).

In 2011, a follow-up study published in Swiss Medical Weekly, concluded that hospital admissions for acute myocardial infarction (AMI) fell 21% in the two years following implementation of the smokefree law in Graubünden, when compared to the two years prior. The researchers also found that changes in outdoor air quality or the use of lipid-lowering drugs did not substantially contribute to the decrease in the incidence of AMI.

Trachsel, L.D.; Kuhn, M.U.; Reinhart, W.H.; Schulzki, T.; Bonetti, P.O., "Reduced incidence of acute myocardial infarction in the first year after implementation of a public smoking ban in Graubuenden, Switzerland," Swiss Medical Weekly, 140(9-10): 133-138, 2010.

Bonetti, P.O.; Trachsel, L.D.; Kuhn, M.U.; Schulzki, T.; Erne, P.; Radovanovic, D.; Reinhart, W.H., "Incidence of acute myocardial infarction after implementation of a public smoking ban in Graubünden, Switzerland: two year follow-up," Swiss Medical Weekly [Epub ahead of print], May 27, 2011.